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A Case of an Immunocompetent Patient with Disseminated Histoplasmosis Presenting with an Oral Lesion

Author(s): Ramsha Saleem and Pillai Anjana

Objective: Presentation of a case of disseminated histoplasmosis in an immunocompetent individual from a non endemic region, in which a mucocutaneous lesion was the presenting sign of infection.

Case: A 38 year old male from Bangladesh who presented with dysphagia and odynophagia for one month. On physical examination, he was noted to have an ulcerative lesion of the left tongue and epiglottis. Biopsy revealed Histoplasma organisms. The patient was successfully treated with amphotericin for ten days as an inpatient and itraconazole as an outpatient.

Conclusion: This case highlights that a diagnosis of infection with fungal organisms, such as Histoplasmosis, must be kept in the differential of mucocutaneous lesions.

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  • Professor of Laboratory of Immunology
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    Gunma University Graduate School of Health Sciences
    Gunma, Japan

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