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Lipid Profile Variations of the Different ABO Blood Group of Apparently Healthy Subjects in Ekpoma

Author(s): Airhomwanbor KO, Idehen IC, OKPARAKU SO, Dic-Ijewere EO, Ehimare RI, Osarobo E, Omolumen LE, Omosun ER

Dyslipidemia is a recognized major risk factors of cardiovascular diseases, but the impact of the different blood groups has not been extensively investigated; at least in Nigeria where the prevalence is on the increase. This study, therefore assesses serum lipid profile among different ABO blood groups in Ekpoma, Nigeria. The study involved 100 subjects comprising of 25 each of blood groups A and B, 15 and 25 subjects with AB and O blood groups respectively. The subjects were male and female within 18-30 years who gave consent and met the inclusion criteria. Following standard procedures blood samples were obtained for serum lipid profile and the results were analyzed using appropriate statistical test (ANOVA) at p<0.05. The results showed that there was no significant difference (p>0.05) in the serum mean total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein and very low density lipoprotein levels in the different blood groups. However, the AB blood group was more likely to present higher lipid variables. There was significant gender differences in HDL in the A and AB blood groups. Judging by the findings of this study, there is likely no marked effect of blood group on serum lipid profile in apparently healthy individuals.

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