Utilization of Cellulose Nanocrystals (CNC) Biopolymer Nanocomposites in Ophthalmic Drug Delivery System (ODDS)

Author(s): Jonathan Tersur Orasugh, Soumyadip Dutta, Diphankar Das, Jyotishka Nath, Chandrika Pal, Dipankar Chattopadhyay

Undeniably drug delivery systems (DDSs) engaged take part in controlling the drug pharmacological effect along with the pharmacokinetic profile with respect to the drug release rate, the site, bioavailability and then the side-effect. Different procedures for visual medication conveyance have been reportedly considered; from fundamental strategies aimed at improving the accessibility of medications; consistency enhancers and mucoadhesives help sedate maintenance and entrance enhancers advance medication transport into the eye. The utilization of drug loaded CNC nanoengineered smart gels enabled medications can be better put where they are required for sustained release of the drugs with straightforward conveyance. Advancements in visual inserts give a way to conquer the physical obstructions that generally forestalled compelling treatment. Advancements are being worked on permitting long term tranquillized conveyance from solitary DDSs: these devices permit the release of the loaded drugs even up to 25 h. Future improvements could lead to the nanoengineering of CNC based drug loaded ODDS with excellent ophthalmic DDSs.