Journal of Bioinformatics and Systems Biology covers the major topics like
• Biomedical image processing, modelling and simulation
• Bio-ontology and data mining, DNA assembly, clustering, mapping
• Computational genomics/proteomics
• Databases, bio-grid, system biology
• Development of algorithmic, mathematical, statistical, modeling
• General in health and medicine
• Parallel algorithms/architectures, computational structural biology
• Phylogeny reconstruction algorithms, physiome, protein structure prediction
• Sequence assembly, search, alignment
• Signal processing
• Signalling/computational biomedical data engineering
• Silico technology
• Simulation, data mining, and computational techniques
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Bioinformatics is an interdisciplinary field that develops strategies and programming tools for understanding natural (biological) information. As an interdisciplinary field of science, bioinformatics consolidates biology, computer science, information engineering, mathematics and statistics to dissect and decipher biological information.
Systems biology is the computational and numerical demonstrating of complex organic frameworks. It is biology-based interdisciplinary field that centers on complex collaborations inside natural frameworks, utilizing an encompassing methodology to organic research. Specifically from 2000, this concept has been in use with biology in wide variety of contexts.
Biomedical image processing
Biomedical image processing is comparable in idea to biomedical signal processing in numerous measurements. It incorporates the investigation, improvement and display of pictures captured through x-ray, ultrasound, MRI, nuclear medicine and optical imaging advances. Image reconstruction and modeling methods permit instant processing of 2D signals to make 3D pictures.
In bioinformatics, sequence assembly alludes to adjusting and consolidating pieces from a more drawn out DNA sequence to remake the first sequence. This is required as DNA sequencing innovation cannot read entire genomes in one go, but instead reads small pieces in the range of 20 and 30000 bases, contingent upon the innovation utilized.
Cluster analysis or clustering is the assignment of collection of objects in a similar group (cluster) is increasingly comparable to one another than to those in different groups (clusters). It is a primary assignment of exploratory information mining, and a typical method for statistical data analysis, utilized in numerous fields, including machine learning, design acknowledgment, picture examination, data recovery, and bioinformatics.
Computational genomics (frequently alluded to as Computational Genetics) alludes to the utilization of computational and statistical analysis to disentangle biology from genome successions and related data, including both DNA and RNA arrangement and in addition other "post-genomic" information (i.e., experimental information acquired with technologies that require the genome sequence, for example, genomic DNA microarrays).
Proteins are substantial biomolecules, or macromolecules, comprising of at least one long chains of amino acid residues. Proteins play out an immense range of capacities inside creatures, including catalyzing metabolic responses, DNA replication, reacting to stimuli, giving structure to cells and living beings, and transporting atoms from one location to other.
Proteomics is the study of proteins. Proteins are crucial parts of living beings, with numerous functions. The proteome is the whole arrangement of proteins that is delivered by a life form or framework. Proteomics has empowered the distinguishing proof of regularly expanding quantities of protein. This changes with time and distinct prerequisites, or stresses that a cell or living being undergoes.
Molecular biology is a part of science that deals with the sub-atomic basis of biological activity between biomolecules in the different frameworks of a cell, including the cooperation between DNA, RNA, proteins and their biosynthesis, and additionally the control of these interactions.
Functional genomics is a field of molecular biology that endeavors to make utilization of the huge abundance of information given by genomic and transcriptomic projects, (for example, genome sequencing tasks and RNA sequencing) to portray gene (and protein) capacities and interactions. In contrast to structural genomics, functional genomics centers on the dynamic viewpoints, for example, gene interpretation, translation, protein-protein interactions.
Structural genomics depicts the 3-dimensional structure of each protein encoded by a given genome. This genome-based methodology takes into account a high-throughput technique for structure assurance by a mix of experimental and modeling approaches.
Nucleic acids are the biopolymers, or small biomolecules, fundamental to every type of life. The term nucleic acid is the general name for DNA and RNA. They are made out of nucleotides, which are the monomers made of three parts: a 5-carbon sugar, a phosphate gathering and a nitrogenous base.
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