Biography

Yunhai Feng published latest article in Drug discovery today entitled An update on the role of nanovehicles in nose-to-brain drug delivery. This article is available in PubMed with an unique identification number PMID: 29330120 and it is published in 2018. The coauthors of this article are Feng Y; He H; Li F; Lu Y; Qi J; Wu W.


Research Interest

Pharmacy


Latest Publication Details

Article Title: An update on the role of nanovehicles in nose-to-brain drug delivery.

Co-Author(s): Feng Y; He H; Li F; Lu Y; Qi J; Wu W

Affiliation(s): Department of Otorhinolaryngology Head & Neck Surgery, Dahua Hospital, Shanghai, China.

PMID 29330120, Year 2018

Abstract: A quantitative analysis has cast doubt over the limited advantages provided by particles for nose-to-brain (NTB) drug delivery. Thus, it is imperative to identify the role of nanovehicles in NTB drug delivery. If nanocarriers are used merely as an option to improve various properties of the drugs or the formulations, it is difficult for them to outperform conventional formulations, such as solutions or gels. However, nanovehicles bring about special features, such as maintenance of the solubilized state of drugs, sustained or delayed release, and enhanced penetration because of surface modifications, all of which lead to enhanced NTB delivery efficiency.

Journal: Drug discovery today

Related Citations

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=pubmed_pubmed&uid=29330120

Related Citations XML

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=pubmed_pubmed&uid=29330120&report=xml

RelatedArticles Review

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=pubmed_pubmed_reviews&uid=28633002