Biography

Shin Hnin Wai published latest article in Echocardiography (Mount Kisco, N.Y.) entitled Assessment of left atrial appendage function by transthoracic pulsed Doppler echocardiography: Comparing against transesophageal interrogation and predicting echocardiographic risk factors for stroke. This article is available in PubMed with an unique identification number PMID: 28849595 and it is published in 2017. The coauthors of this article are Wai SH, Kyu K, Galupo MJ, Songco GG, Kong WKF, Lee CH, Yeo TC, Poh KK.


Research Interest

Cardiology, Cardiovascular Medicine.


Latest Publication Details

Article Title: Assessment of left atrial appendage function by transthoracic pulsed Doppler echocardiography: Comparing against transesophageal interrogation and predicting echocardiographic risk factors for stroke.

Co-Author(s): Wai SH, Kyu K, Galupo MJ, Songco GG, Kong WKF, Lee CH, Yeo TC, Poh KK

Affiliation(s): Department of Cardiology, National University Heart Center Singapore, National University Health System, Singapore.

PMID 28849595, Year 2017

Abstract: Transesophageal echocardiographic (TEE) findings of left atrial appendage (LAA) thrombus, spontaneous echo contrast (SEC), and LAA dysfunction are established risk factors of cardioembolic stroke. The semi-invasive nature of TEE limits its utility as a routine risk stratification tool. We aim to correlate TEE and transthoracic echocardiography (TTE) pulsed Doppler measurements of LAA flow velocities and use TTE measurements to predict TEE findings.We prospectively measured pulsed Doppler LAA flow velocities in 103 consecutive patients on TEE and TTE. There was a strong correlation between TEE and TTE LAA emptying velocity (LAA E) (r = .88, P < .001) and a moderate correlation between LAA filling velocities (r = .50, P < .001). TTE LAA E predicted the presence of thrombus or SEC independent of atrial fibrillation (AF). To predict the presence of thrombus or SEC, the optimal TTE LAA E cutoff was ?30 cm/s in all patients (75% sensitive, 90% specific) and ?31 cm/s in AF patients (80% sensitive, 79% specific). To predict LAA dysfunction (TEE E ? 20 cm/s), the optimal TTE LAA E cutoff was ?27 cm/s (100% sensitive, 89% specific in all patients and 100% sensitive, 74% specific in AF patients).TTE assessment of LAA function is feasible and correlates well with the more invasive TEE method. It predicts the presence of thrombus, SEC, and LAA dysfunction on TEE. TTE LAA assessment has incremental value in thromboembolic risk stratification and should be utilized more frequently.

Journal: Echocardiography (Mount Kisco, N.Y.)