ExoTMS™ Technology: A Novel Breakthrough in Transcranial Magnetic Stimulation for Enhancing Mental Well-Being

Author(s): Michelle Dees, Yael Halaas, JD McCoy

Background: Mental well-being encompasses emotional, psychological, and social health. In today’s world, new stressors and challenges continue to emerge, contributing to a decline in overall well-being. This study aims to evaluate the effects of ExoTMS™ brain stimulation technology on enhancing mental well-being and assessing subject satisfaction, therapy comfort, and procedural safety. Methods: 33 subjects (n= 33, 26 females, 7 males, 49.8±15.1 years) received 4 ExoTMS™ sessions. The Warwick-Edinburgh Mental Well-Being Scale (WEMWBS) was used to assess mental well-being at baseline, after the final treatment, and at the 1-month and 3-month follow-ups. Subject satisfaction, therapy comfort and procedural safety were also recorded. Results: The observed changes in WEMWBS scores were statistically significant (p<0.001), with an average increase of 6.7±6.4 points post-treatment, 7.6±8.0 points at 1 month, and 6.8±8.0 points at 3 months. The percentage of participants experiencing an increase in WEMWBS scores was 78.8% post-treatment, 84.8% at 1 month, and peaked at 87.5% at 3 months. Subjects self-reported improvements in mood, confidence, mental energy, the feelings of stress, depression, anxiety, as well as sleep onset and quality. 90.9% of subjects found the treatments comfortable. Conclusion: The study results indicate ExoTMS™ treatments as a promising approach in enhancing mental well-being, showing efficacy across all WEMWBS well-being categories, from low to high. The non-invasive treatment reached significant results with four sessions, while ensuring high therapy comfort and subject satisfaction.