Pseudo-Pseudo Meigs’ Syndrome in a Patient with Systemic Lupus Erythematosus Flare

Author(s): Muhammad Sohaib Asghar, Abubakar Tauseef, Maryam Zafar, Hiba Shariq, Mariam Amir, Uzma Rasheed, Nimra Shaikh, Gul Muhammad Memon

Pseudo-pseudo Meig’s syndrome (PPMS) is an exceedingly uncommon disease in patients with diagnosed systemic lupus erythematosus (SLE) or mixed connective tissue disease (MCTD). This is a case report of a 23-year-old woman with a history of systemic lupus erythematosus (SLE), presented with rapidly increasing abdominal girth, facial/pedal edema, oliguria, and dyspnea, who was presumed to be developing pre-eclampsia in her 35th week of gestation. She was managed by an emergency Cesarean-section, and an incidental finding of peri-operative ascitic fluid was obtained and a right-sided pleural effusion. Upon further investigations, her CA-125 levels were found to be elevated. Her anti-double-stranded DNA titers were increased whereas complement levels (C3 and C4) were reduced indicating SLE flare. All these features suggested the diagnosis of pseudo-pseudo meig’s syndrome, a rare condition associated with SLE. It is asserted in our case that her pregnancy triggered the lupus flare.