A Rare Occurrence of an Intraosseus Squamous Cell Carcinoma in Association with Squamous Odontogenic Tumor of Mandible
Author(s): Nilesh D Pardhe, Pradakhshana Vijay, Manika Arora and Nikunj Mathur
Squamous odontogenic tumor (SOT) reported for the first time by Pullon et al in 1975was described and classified as a distinct pathological entity by the World Health Organization (WHO) in 1992 . A rare benign neoplasm, it can locally infiltrate and extend to neighboring structures such as the maxillary sinuses and nasal cavity. Clinically it presents itself as an asymptomatic swelling in the alveolar process, with most cases being accidentally reported on routine dental radiographs . Histologically, it is composed of well-differentiated squamous epithelium in a fibrous stroma . Published scientific literature accounts for approximately 47 cases of SOT . Considering the rarity of this tumor, the malignant transformation of this benign tumor is even rarer with only 2 cases reporting its occurrence [4, 5]. To the best of author’s knowledge, malignant transformation of SOT into squamous cell carcinoma (SCC) is the first to be documented from the South-East Asian subcontinent. We herein report an extremely rare occurrence of SOT with malignant transformation exhibiting an aggressive bone destruction of mandible.