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Essential Hypertension: Pathophysiology& Management (Current View)

Author(s): Tarun Saxena, Azeema Ozefa Ali, Manjari Saxena

The rising burden of essential hypertension necessitates the need for further understanding of pathophysiology. Recent studies have focused upon sympathetic over-activity. Sympathetic overactivity is associated with increased left ventricular contractility and various mechanisms of hypertension. Disturbed cortical impulses (stress) to the hypothalamus shifts the vasomotor center to a higher level resulting in increased basal sympathetic discharge and hypertension.


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