Severe Generalized Sweet Syndrome with good outcome: A Case Report

Author(s): Migena Vargu, Petrit Vargu, Sabina Dedej, Eriselda Kurushi, Samuele Vargu, Alecia Anyim, Elsie Tachie Mensah, Ibrahim Gowaily, Jaclyn Tan-Wohlers, Grace Lin, Gurparneet Kaur Sohi, Abdelrahman Awad, Henri Fero, Yousra Abdalla, Alma Lamo, Juna Musa

Sweet syndrome (SS), also known as acute febrile neutrophilic dermatosis, is characterized by fever, elevated white blood cell counts predominantly composed of neutrophils, painful red plaques on the skin, and dermal neutrophilic infiltration without vasculitis. SS can be triggered by various factors and is diagnosed based on clinical, laboratory, and histopathological criteria. SS is classified into three types: classical (or idiopathic), malignancy-associated, and drug-induced. Classical Sweet syndrome is the most common form, often linked to infectious diseases, inflammatory disorders, or pregnancy. This case report describes a patient with an aggravated and generalized form of Sweet syndrome who had a favorable outcome following appropriate treatment.