Prolonged Treatment with Ceftriaxone Cures A Patient with Chronic Lyme Disease

Author(s): Alexis Lacout, Christian Perronne, Michel Franck

This is the case of a 40-year-old immunocompetent, female patient presenting with a "polymorphic persistent syndrome after a possible tick bite" (SPPT), a syndrome officially recognized by the French High Authority for Health (HAS). This patient presented with polymorphic symptoms and was unable to walk without a walker. Only ceftriaxone was effective. She experienced several episodes of remission and relapse, when treatments were started and stopped. Finally, it was possible to achieve a prolonged final remission, persisting for 3 years after the last anti-infective treatments had been stopped.