Abstracting and Indexing

  • Google Scholar
  • CrossRef
  • WorldCat
  • ResearchGate
  • Academic Keys
  • DRJI
  • Microsoft Academic
  • Academia.edu
  • OpenAIRE

COVID-19 Diagnosis based on Taste Disorders: A Case-Control Study

Author(s): Kamil Adamczyk, Michal Herman, Janusz Fraczek, Robert Piec, Barbara Szykula-Piec, Artur Zaczynski, Rafal Wójtowicz, Krzysztof Bojanowski, Ewa Rusyan, Zbigniew Kró, Waldemar Wierzba, E

Background: We aimed to assess taste disturbances in COVID-19 patients. Additionally, we hypothesized that it is possible to establish a reliable and inexpensive screening method for SARS-COV-2 infection using a flavor test.

Methods: The ability to taste the sweet, salty, sour and bitter flavors was assessed in 52 COVID-19 patients and 36 controls using flavor tablets (sucrose, NaCl, ascorbic acid and grapefruit extract - 99% naringin) with flavor concentrations established previously in healthy subjects.

Results: Subjective smell or taste disturbances were reported by 65% of subjects in the test group compared with 8% in the control group. A numerical difference was demonstrated for all flavor tests recognitions between COVID-19 patients and the control group; however, the difference was only significant with the sweet and salty flavor tablets. Complete ageusia was very uncommon in the study group and occurred in only 1 out of 52 subjects. Only one predictive model – the medical questionnaire, consisting of questions regarding self-reported loss of taste, smell, or fever - displayed good performance in COVID-19 diagnosis (ROC AUC = 0.82). The performance of other predictive models, including the taste testers, was lower.

Conclusion: Among all tested flavors, the sweet and salty flavors perception was impaired in COVID-19 patients. Despite the objective taste tests being carried out, the medical questionnaire was the predictive model with the best performance, higher than any single taste test or even multiple tastes test.

Grant Support Articles

© 2016-2022, Copyrights Fortune Journals. All Rights Reserved!