Klebsiella Pneumoniae Urinary Tract Infection Seen in the Laboratory of the University Hospital of Befelatanana
Author(s): Lalaina Mamenosoa Rakotondraoelina, Zafindrasoa Domoina Rakotovao-Ravahatra, Solofo Sarah Rafaramalala, Andriamiadana Luc Rakotovao, Andry Rasamindrakotroka
Background: Klebsiella pneumoniae (K. pneumoniae) urinary tract infections (UTIs) are common in the community and in hospital. The aims of this study were to evaluate antibiotic resistance and to describe the factors associated with urinary tract infections caused by K. pneumoniae.
Methods: This is a descriptive and cross-sectional study of 524 results of cytobacteriological examinations of urine (CBEU) of pus over a period of 8 months, from January 2022 to August 2022, at the laboratory of the University Hospital of Befelatanana.
Results: Among the 524 CBEU, 157 cases were positive showing a hospital prevalence of 30% of UTI. Among the germs identified, 18 cases (3.4%) were represented by isolates of K. pneumoniae. Regarding the associated factors, subjects aged 60 and over (5.7%) (p=0.20; NS), men (11%)(p=0.07), patients with urinary disorders (13%)(p=0.001) and hospitalized in Internal Medicine departments (9%) (p=0.44; NS) were the most affected by K. pneumoniae UTI. Concerning the results of the antibiograms, the resistances of the isolates of K. pneumoniae varied from 5.6% (amikacin) to 100% (amoxicillin).
Conclusion: Systematic CBEU should be performed in vulnerable hospitalized patients with urinary signs to ensure rapid and effective management of K. pneumoniae UTI. Similarly, hygiene measures must be improved in hospitals in order to reduce the occurrence of nosocomial UTI due to multi-resistant K. pneumoniae.