Abstracting and Indexing

  • PubMed NLM
  • Google Scholar
  • CrossRef
  • WorldCat
  • ResearchGate
  • Academic Keys
  • DRJI
  • Microsoft Academic
  • Academia.edu
  • OpenAIRE

Risk factors for nine-year mortality of elderly patients with cognitive impairment at admission

Author(s): Hiroshi Yamamoto, Kenichi Ogawa, Yasushi Hisamatsu, Kazuo Matsuo, Hideyo Yamamoto, Tatsuya Ishitake

Background: Dementia can be a major cause of mortality and morbidity in geriatric patients. It is thus essential to assess their mental state at an early stage.
Aims: We appraised the impact on mortality and hospital outcomes using the revised simplified short-term memory recall test (STMT-R) with simultaneous collection of clinical data.
Methods: The subjects were 612 acute inpatients ≥65 years old encountered from December 2014 to September 2015. Following the collection of clinical data, the survival was subsequently measured for eight to nine years until December 2023. An STMT-R score of ≤4 was considered to indicate cognitive dysfunction. To explore the association between the risk factors and mortality in cognitive impairment subjects, the Kaplan-Meier method and Cox’s proportional hazards regression models were used to examine mortality and survival rates.
Results: The mean age of the subjects was 82.1 (±7.94) years old, and 55.9% were female. The cognitive function was classified into three categories according to severity: Incomplete Testing Group (Incomplete), Cognitive dysfunction Group (Abnormal) and Non-Cognitive dysfunction Group (Normal). A total of 325 patients (51.5%) died during follow-up. The Kaplan-Meier and the log-rank tests showed a negative prognostic effect of cognitive impairment, malnutrition, pneumonia and cancerbearing state (p<0.01). After adjusting for potential covariates, the Cox regression analysis showed that the mortality hazard is increased for “Incomplete” (hazard ratio 3.53; 95% confidence interval 2.39-5.21 p<0.0001) and “Abnormal” (hazard ratio 1.68; 95% confidence interval 1.21-2.32 p<0.01).
Conclusion: Malnutrition, hypoalbuminemia and a cancer-bearing state can significantly decrease the survival rate in patients with cognitive impairment at admission. Cognitive impairment also has an independent impact on survival rate in acutely ill geriatric patients.

Journal Statistics

Impact Factor: * 3.8

Acceptance Rate: 77.96%

Time to first decision: 10.4 days

Time from article received to acceptance: 2-3 weeks

Discover More: Recent Articles

Grant Support Articles

© 2016-2025, Copyrights Fortune Journals. All Rights Reserved!