An Unusual Metastatic Signet-ring Cell Carcinoma of the Rectosigmoid Colon Presenting as Mandibular Tumor in a Female patient: A Case Report and Review of the Literature

Author(s): Kuang-Ting Liu, Yueh-Ching Chang, Yu-Chieh Lin, Junn-Liang Chang

Background: Metastatic adenocarcinomas of the colon to the oral cavity are very uncommon, especially signet-ring cell carcinoma (SRCC) is relatively extremely rare, and constitutes about 1% of all oral malignancies.

Case Presentation: A 54-year-old female who had been diagnosed with SRCC of the rectosigmoid (RS) colon with peri-colic nodal metastasis after initial low anterior resection (LAR). Then, she has performed completely 12 cycles of palliative adjuvant chemotherapy. Two years later, she presented a progressively swelling painful mass in the right mandible and incisional biopsy was performed. Histopathology examination demonstrated metastatic SRCC of the RS colon to the right mandible bone diagnosed in an incisional biopsy. Three months after the definite diagnosis of the right mandibular lesion, she died of the disease because she represented an incurable disseminated disease.