cProSite: A Web Based Interactive Platform for Online Proteomics, Phosphoproteomics, and Genomics Data Analysis

Author(s): Dunrui Wang, Xiaolan Qian, Yi-Chieh Nancy Du, Beatriz Sanchez-Solana, Kailing Chen, Madhu Kanigicherla, Lisa M Jenkins, Jason Luo, Sarah Eng, Brian Park, Ben Chen, Xiaozheng Yao, Thuong Nguyen, Brajendra K Tripathi, Marian E Durkin, Douglas R Lowy

We developed cProSite, a website that provides online genomics, proteomics, and phosphoproteomics analysis for the data of The National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (CPTAC). This tool focuses on comparisons and correlations between different proteins and mRNAs of tumors and normal tissues. Our website is designed with biologists and clinicians in mind, with a user-friendly environment and fast search engine. The search results of cProSite can be used for clinical data validation and provide useful strategic information to identify drug targets at proteomic, phosphoproteomic, or genomic levels. The site is available at http://cprosite.ccr.cancer.gov.