Metastatic Dermatofibrosarcoma Protuberans in a Young African Lady: A Case Report

Author(s): Motsepe TA, Maritz SM

Dermatofibrosarcoma protuberans (DFSP) is a rare tumour that originates from the dermal fibroblasts. It is often a benign lesion with a low metastatic potential. However, if left untreated, it can become locally aggressive and infiltrate surrounding fascia, muscles and bones. Distant metastases, though uncommon, are usually to the lungs with lymph node involvement being extremely rare. Below is a case of a young African lady who at presentation had a locally advanced DFSP with extensive metastases to distant lymph nodes and the lungs.

Contribution: The overall prognosis of DFSP is favourable with an excellent cure rate post surgical excision. However, with locally advanced tumours and with distant organ metastases cure becomes a non-feasible option. Therefore early diagnosis before tumour growth acceleration is key to a satisfactory patient outcome.