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Incidence of Neoplasms after Appendectomy in a Cohort of 1197 Patients

Author(s): Stravodimos C, Greiber A, Riemenschneider F, Popp A, Schön MR, Justinger C

Objective: Appendectomy is the gold standard in the treatment of acute appendicitis. The objective of this study was to investigate the incidence of unexpected histopathological findings after appendectomy in a large cohort of patients.

Methods: We retrospectively analyzed the demographic and histopathologic data of 1197 patients, who underwent an appendectomy in order to treat an initially diagnosed acute appendicitis between January 2012 and December 2017. Patients undergoing an appendectomy during other surgical procedures as well as patients under 18 years of age were excluded from the study.

Results: Out of 1197 patients in total who underwent an appendectomy, 1124 (93.9%) received a laparoscopic procedure and 73 (6.1%) underwent a conventional appendectomy. The obtained specimen presented with the following histopathological findings: 103 (8.6%) cases of catarrhal inflammation, 722 (60.3%) cases of suppurative acute appendicitis and 217 (18.1%) of gangrenous acute appendicitis. Furthermore, in 28 (2.3%) cases there were unexpected histopathological findings. Here, neoplasms were found in 25 (2.1%) cases: 16 cases of LAMN (low grade appendice

Conclusions: Unexpected histopathological findings in appendectomy specimens including neoplasms are not rare (2.3%). Histopathological assessment allows early diagnosis and treatment of these incidental findings.

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